Sunday October 27

16:00-18:00

Registration desk open

18:30-19:30

Conference opening: Dr Robert Sackstein (Florida International University, Miami, USA)

O1. Cell Surface Glycoengineering:  Applying GPS to CAR T-cells.

19:30-22:00

Reception

Monday October 28

8:00-8:45

Registration-Mounting of posters

8:45-9:00

Welcome to the 30th Joint Meeting

François Foulquier, Sophie Groux-Degroote, Marie-Ange Krzewinski-Recchi (UGSF, Lille, France)

SESSION 1

Glycobiotechnology                                            Chair : Stéphane Vincent

9:00-9:35

Invited Lecture: Pr. Manfred Wuhrer (Leiden University Medical Center, Leiden, the Nederlands)

O2. N-glycome signatures in human plasma: associations with physiology and major diseases.

9:35-9:55

Joost Snijder (Utrecht)

O3. Integrating MS and cryoEM to monitor glycosylation of viral antigens and its role in antigen-antibody interactions.

9:55-10:15

Johannes Gottschalk (Aachen)

O4. Comprehension and regulation of one-pot enzymatic synthesis of high molecular weight hyaluronic acid.

10:15-10:35

Angela van Diepen (Leiden)

O5. Glycomic analysis of the filarial nematode Brugia malayi and characterization of anti-glycan antibody responses during infection.

10:35-11:00

Coffee break

11:00-11:20

Manuel Dauchez (Reims)

O6. Umbrella Visualization: a 3D tool bringing valuable information about proteins/glycosylations interplay.

11:20-11:40

Viktoria Heine (Aachen)

O7. Directing fucose to the desired binding site – reaction of bacterial α1,3-fucosyltransferases with di-N-acetyllactosamine (di-LacNAc).

11:40-12:00

Mathieu Decloquement (Lille)

O8. Molecular phylogeny and exogenous sialylation approaches identify a novel α2,8-sialyltransferase in zebrafish: ST8Sia VIII.

12:00-12:06

Sponsor presentations (2min talk) e-Zyvec, Glycodiag and PAGès

12:06-13:30

Lunch break and poster session

SESSION 2

Glycans and diseases                                       Chair : Dulce Papy-Garcia

13:30-14:05

Invited Lecture: Prof Celso Reis (IPATIMUP, Porto, Portugal)

O9. Altered glycosylation in Cancer – targeting tumor heterogeneity and therapeutic implications.

14:05-14:25

Ninon Very (Lille)

O10. O-GlcNAcylation of Thymidylate Synthase: a new regulatory mechanism of 5-Fluorouracil chemotherapy response in colorectal cancer?

14:25-14:45

Veronika Weber (Halle (Saale))

O11. The effect of glycation on the permeability of human blood-brain barrier.

14:45-15:05

Erika Coletto (Norwich)

O12. The role of mucin glycosylation in the communication between the gut microbiota and the brain.

15:05-15:25

Anne-Sophie Roy (Lille)

O13. The lack of SPCA1 functionality in Hailey-Hailey disease patients’ cells leads to a hyper Mn2+-induced TMEM165 sensitivity (towards a new tool to easily diagnose these patients).

15:25-15:45

Walid Haouari (Paris)

O14. Bikunin proteoglycan isoforms are convenient serum biomarkers of inherited defects in glycosaminoglycan biosynthesis and Golgi homeostasis.

15:45-16:45

Coffee break - Poster session

16:45-17:20

Invited Lecture: Dr Vincent Cantagrel (Institut Imagine, Paris, France)

O15. Defective protein N-glycosylation and brain development.

17:20-17:50

Business Meeting of the Societies

19:30

Dinner (Hermitage Gantois, Lille)

Tuesday October 29

Session 3

Glycoimmunology                                             Chair : Cornelis H Hokke

9:00 - 9:35

Invited Lecture: Pr. Ivan Martinez Duncker (Universidad Autónoma del Estado de Morelos, Cuernavaca, Mexico)

O16. CD4+ T cells: Looking out for that α2,8 sialic acid.

9:35 – 9:55

Tao Zhang (Leiden)

O17. Glycosphingolipid repertoire profiling delineates regulation of receptor-ligand interactions.

9:55 - 10:15

Kim F. Bornhöfft (Dummerstorf)

O18. Bovine cervical mucins inhibit the release of Neutrophil Extracellular Traps (NETs) in a sialic acid-dependent manner.

10:15 - 10:35

Samir Jawhara (Lille)

O19. Fungal Chitin Treatment Restores the Anaerobic Bacteria and Reduces the Intestinal Inflammation in Mice.

10:35 – 11:35

Coffee break and poster session

SESSION 4

Glycans in host-pathogen interactions            Chair : Robert de Vries

11:30 - 11:50

Franz-Georg Hanisch (Cologne)

O20. Oligosaccharides and Viral Infection: Human Milk Oligosaccharides versus Algal Fucan-type Polysaccharide.

11:50 - 12:10

Lin Shen (Lille)

O21. GlfH1, an endogenous remodeling galactofuranosidase that hydrolyzes mycobacterial arabinogalactan.

12:10 – 12:30

Dimitrios Latousakis (Norwich)

022. Serine-rich repeat protein adhesins from Lactobacillus reuteri display strain specific O-glycosylation profiles.

12:30-13:00

Concluding remarks, 31th Joint Meeting announcement and poster awards

13:00-14:00

Lunch